Intravitreal Bevacizumab for Choroidal Metastasis of Lung Carcinoma; a Case Report

Purpose: to report an alternative treatment for metastatic tumors within the eye. case report: five intravitreal injections of bevacizumab (2.5 mg each) were performed in one eye of a 50-year-old woman with choroidal metastasis of lung carcinoma. tumor size was reduced, pain disappeared, vision improved, and there were no secondary reactions. vision improved from 20/40 to 20/20 and metamorphopsia decreased. ten months after initiating treatment, an ultrasonographic study revealed no residual tumor, the choroid was normal in thickness and fluorescein angiography revealed a scar but no mass lesion. conclusion: intravitreal bevacizumab displayed beneficial effects in reducing tumor size and improving symptoms in this case of choroidal metastasis of lung carcinoma. the antineoplasic properties of this agent make it a viable alternative for treatment of metastatic choroidal tumors