Vitrectomy for Diffuse Refractory Diabetic Macular Edema Associated with a Taut Premacular Posterior Hyaloid

Purpose: to evaluate the anatomic and visual results and complications of vitrectomyin eyes with diffuse refractory diabetic macular edema associated with a taut posteriorhyaloid.methods: this prospective interventional case series was conducted on 25 eyes of 22 patients with diffuse refractory clinically significant diabetic macular edema, macularthickness greater than 250 ìm on optic coherence tomography (oct) and thickened posterior hyaloid. best-corrected visual acuity (bcva) and macular thickness measuredby oct were evaluated preoperatively and repeated 3 and 6 months postoperatively.macular perfusion was evaluated by fluorescein angiography, pre- and six monthspostoperatively.results: mean bcva was 1.14±0.51 logmar, preoperatively which improved to0.89±0.53 logmar six months postoperatively (p=0.005). mean preoperative macularthickness was 506±121.9(mu)m which decreased to 318±90.5 ìm, six monthspostoperatively (p=0.001).conclusion: vitrectomy and removal of the posterior hyaloid membrane appearsbeneficial in eyes with diffuse diabetic macular edema unresponsive to laser therapyand a taut premacular posterior hyaloid.