Outcomes of Lensectomy in Hereditary Lens Subluxation

Purpose: to evaluate the results of pars plana lensectomy in patients with hereditarylens subluxation.method: hospital records of patients with hereditary lens subluxation who had undergonepars plana lensectomy at labbafinejad medical center, tehran-iran from 1996 to2003 were reviewed. patients with more than 6 months of follow up were included.underlying disorders, best corrected visual acuity (bcva) before and after surgery,intraocular pressure (iop), postoperative refraction and complications were evaluated.results: overall, records of 87 eyes of 49 patients including 27 male and 22 female subjects were reviewed. mean follow up duration was 20 ±18 months. underlying disordersleading to lens subluxation included marfan syndrome (79.5%), weill-marchesani syndrome(8.2%), simple ectopia lentis (8.2%), and homocystinuria (4.1%). the most commonindication for surgery was non-correctable refractive error (92.1%). mean bcva was1.13 logmar (20/250) preoperatively, which improved to 0.26 logmar (20/30-20/40)postoperatively (p<0.001). bcva ≥20/40 was achieved in 82.8% of cases after surgery.angle-supported anterior chamber intraocular lens (aciol) was implanted in 85.1% ofthe eyes. prophylactic band was applied in 63 eyes (72.4%). retinal detachment developedin four eyes (4.6%) and was successfully treated.conclusions: lensectomy/anterior vitrectomy with implantation of an angle-supportedaciol in patients with hereditary lens subluxation improves vision significantly without considerable complications.