Hydrophilic acrylic intraocular lens opacification after descemet stripping automated endothelial keratoplasty

Purpose: to report hydrophilic acylic intraocular lens (iol) opacification after descemet stripping automated endothelial keratoplasty (dsaek) in an eye with multiple prior intraocular surgeries and iatrogenic aniridia. case report: a 34-year-old woman with history of penetrating keratoplasty (pkp) for advanced keratoconus and subsequent urrets-zavalia syndrome (uzs) underwent phacoemulsification and hydrophilic acrylic iol implantation for her cataract. in order to control post-pkp glaucoma,multiple glaucoma surgeries including two glaucoma drainage implants were performed. as the original corneal graft failed,the patient subsequently underwent re-pkp. four years later,she underwent dsaek for treatment of the second graft failure. ten months after dsaek,a double semi-circular pattern of iol opacification was observed on the anterior surface of the iol. the patient did not report any complaints and we decided not to exchange the iol. conclusion: in an eye with uzs and iatrogenic aniridia,iol opacification may result from direct contact between the iol surface and exogenous air. aniridia can be a risk factor for development of iol opacification after dsaek. further studies are required to confirm this hypothesis. © 2016 journal of ophthalmic and vision research.