مختصات روان سنجی پرسش نامه زمینه‌یابی سلامت (Sf-36) برای استفاده در مولتیپل اسکلروزیس: ارزیابی روان سنجی در بیماران ایرانی

Background and objectives: quality of life assessment as an outcomes measure in multiple sclerosis (ms) can have a key role in identifying adverse effects of the disease and the impact of different treatments in the progress and improvement of patients; hence, the aim of this study was to examine the psychometric characteristics persian version of the health survey questionnaire (sf-36) in the ms.subjects and methods: one hundred and sixty two patients were selected by consecutive method. sf-36 was evaluated for its internal consistency reliability, construct validity, concurrent, predictive and differentiation. in order to achieve this aim, the fatigue severity scale and the 21-question (dass-21) of depression, anxiety and stress scale were used.results: internal consistency of sf-36 subscales except social functioning and emotional problems (?= 0.42 to 0.93) were favorable. analysis of the validity of the sf-36 showed that all of the questionnaire items had a strong positive correlation with subscales on their own (r=0.48 to 0.95); each subscale had a strong and inverse correlation with the constructs of fatigue, depression, anxiety and stress (r= -0.27 to -0.71 ; p < 0.001); sf-36 physical component predicted a significant proportion of the variance in score on fatigue (p < 0.0001) and mental component also showed a significant proportion of the variance in scores on depression, anxiety and stress, even after controlling demographic confounding factors of age, sex, marital status and educational level (p < 0.0001). the mean of all subscales was significantly greater in both groups of abnormal and fatigued patients than normal and nonfatigued patients.conclusion: persian version of the sf-36 has good validity and reliability and could be used to assess the impact of ms outcomes on quality of life of patients.