تعیین ارتباط رنوواسکولار امپدنس با وجود و درجه بندی واریس های مری در بیماران سیروز کبدی

Background and objective: bleeding from esophageal varicose (ev) is one of the lethal complications of liver cirrhosis. upper gastro-intestinal endoscopy (ugie) is performed in all cirrhotic patients for screening ev but recently some non-invasive methods have been evaluated as a substitute. for this purpose the aim of this study was to assess the correlation between ev and reno-vascular resistance index (rri) in cirrhotic patients.subjects and methods: sixty four cirrhotic patients with normal renal function were included and underwent ugie ‎and measuring rri using color flow and pulsed wave doppler ultrasonography. correlation ‎ between the mean of rri was evaluated with presence and grade of ev. p < 0.05 was considered statistically significant. results: ev was detected in 42 patients (65.5%). the means of rri were 0.68±0.03 versus 0.62±0.04 in patients with or without ev, respectively (p < 0.001). moreover, there was a significant statistically difference between the mean of rri and size of ev (p=0.04). the cutoff points for prediction of ev were: higher than 0.67, had sensitivity, specificity, positive and negative predictive values of 73.8, 72.7, 83.8 and72.8%, respectively. there was a positive association between the child-pugh class and presence of ev (p =0.038). in contrast, no correlation between the child-pugh class and grade of ev was detected (p =0. 31).conclusion: these data suggest that the extent of rri has strong correlation with the presence and degree of ev in cirrhotic patients. consequently, rri may be consider as alternative non-invasive marker for screening ev specially in patients with child-pugh class a cirrhosis.