مقایسه( global longitudinal peak systolic strain (glps و عملکرد سیستولیک و دیاستولیک بطن چپ در افراد با الگوی رپولاریزیشن زودرس در الکتروکاردیوگرام و بیماران انفارکتوس میوکارد بوسیله اکوکاردیوگرافی speckle tracking

زﻣﯿﻨﻪ و ﻫﺪف: ارزﯾﺎﺑﯽ (glps) global longitudinal peak systolic ﯾﮏ روش دﻗﯿﻖ و ﻗﺎﺑﻞ ﺗﮑﺮار ﺑﺮای ﺑﺮرﺳﯽ ﻋﻤﻠﮑﺮد ﺳﯿﺴﺘﻮﻟﯿﮏ ﺑﻄﻦ ﭼﭗ اﺳﺖ. اﯾﻦ ﻣﻄﺎﻟﻌﻪ ﺑﺎ ﻫﺪف ﻣﻘﺎﯾﺴﻪ glps اﻓﺮاد ﺑﺎ اﻟﮕﻮی er در ecg ﺑﺎ ﺑﯿﻤﺎران اﻧﻔﺎرﮐﺘﻮس ﻣﯿﻮﮐﺎرد ﺑﺎ ﺑﺎﻻ رﻓﺘﻦ ﻗﻄﻌﻪ stemi) st) و اﻓﺮاد ﺳﺎﻟﻢ ﺑﻮﺳﯿﻠﻪ اﮐﻮﮐﺎردﯾﻮﮔﺮاﻓﯽspeckle tracking اﻧﺠﺎم ﺷﺪ. روش ﺑﺮرﺳﯽ: اﯾﻦ ﻣﻄﺎﻟﻌﻪ ﮐﻨﺘﺮل-ﻣﻮردی ﺑﺮ روی 30 ﺑﯿﻤﺎر stemi، 19 ﻓﺮد دارای اﻟﮕﻮی er در ecg ﻣﺮاﺟﻌﻪ ﮐﻨﻨﺪه ﺑﻪ ﺑﯿﻤﺎرﺳﺘﺎنﻫﺎی اﻣﺎم و ﮔﻠﺴﺘﺎن اﻫﻮاز اﻧﺠﺎم ﺷﺪ. ﮔﺮوه ﮐﻨﺘﺮل ﺷﺎﻣﻞ 30 ﻓﺮد ﺳﺎﻟﻢ، ﺑﺪون ﺑﯿﻤﺎری ﻗﻠﺒﯽ ﻋﺮوﻗﯽ و دارای ecg ﻧﺮﻣﺎل ﺑﻮد. اﻟﮕﻮی er ﺑﻪ ﻋﻨﻮان notch ﯾﺎ slur در اﻧﺘﻬﺎی ﮐﻤﭙﻠﮑﺲ qrs، اﻓﺰاﯾﺶ mv ≤ j-point 0/1 در ﺑﯿﺶ از دو ﻟﯿﺪ ﭘﯿﻮﺳﺘﻪ در ecg و qrs <120 ms ﺗﻌﺮﯾﻒ ﺷﺪ. ﺗﻤﺎم اﻓﺮاد ﺳﻪ ﮔﺮوه ﺑﺮای ارزﯾﺎﺑﯽ ﻋﻤﻠﮑﺮد ﺳﯿﺴﺘﻮﻟﯿﮏ و دﯾﺎﺳﺘﻮﻟﯿﮏ ﻗﻠﺒﯽ ﺗﺤﺖ اﮐﻮﮐﺎردﯾﻮﮔﺮاﻓﯽ 2d ste ﻗﺮار ﮔﺮﻓﺘﻨﺪ. ﯾﺎﻓﺘﻪﻫﺎ: ﻣﯿﺰان st elevation در ﺑﯿﻤﺎران stemi ﺑﻪ ﻃﻮر ﻣﻌﻨﯽداری ﺑﯿﺸﺘﺮ از ﮔﺮوه er ﺑﻮد )1/50 ± 1/68 در ﻣﻘﺎﺑﻞ 0/67 ±1/68 ؛ 0/001p). ﻫﻤﭽﻨﯿﻦ ﺑﺮوز اﺧﺘﻼل ﻋﻤﻠﮑﺮد دﯾﺎﺳﺘﻮﻟﯿﮏ ﺑﻄﻦ ﭼﭗ (lvdd grade 1) در ﮔﺮوه stemi ﺑﯿﺸﺘﺮ از دو ﮔﺮوه er و اﻓﺮاد ﺳﺎﻟﻢ ﺑﻮد (ﺑﻪ ﺗﺮﺗﯿﺐ 10/5 ،%60 % و 9/7 % ؛ 0/001

Comparison of Global longitudinal peak systolic strain (GLPS) and left ventricular systolic and diastolic function in subjects with early repolarization pattern in ECG and patients with myocardial infarction by speckle tracking echocardiography

Introduction:The aim of this study was to comparison of GLPS in subjects with ER pattern in ECG with patients with STEMI and healthy subjects by speckle tracking echocardiography. Methods: This casecontrol study was conducted on 30 patients with STEMI and 19 subjects with ER pattern on ECG admitted to Imam and Golestan hospitals in Ahvaz. The control group was consisted of 30 healthy subjects without cardiovascular disease and with normal ECG. ER pattern, defined as notching or slurring of the terminal part of QRS complex, Jpoint elevation ≥0.1 mV in more than 2 contiguous leads on ECG and QRS Results: STsegment elevation was greater with STEMI group versus ER group (3.57 ± 1.50 vs. 1.68 ± 0.67; p< 0.001). The patients with STEMI had a significant lower ELVF (p< 0.001), SV (p< 0.001), TAPSE (p< 0.001) and LV GLPS (p< 0.001) and higher HR (p< 0.001) and PAP (p< 0.001) compared to ER and control groups, while there was no significant difference between the control and ER group (P>0.05). Mmoreover, the incidence of Left ventricular diastolic dysfunction (LVDD grade 1) in the STEMI group was higher than in two groups of ER and healthy (60%, 10.5% and 9.7%, respectively; P <0.001). Conclusions: Echocardiography parameters including LVEF, PAP, HR, SV, TAPSE, GLPS and LVDD could be used to differentiate between STEMI and people with ER pattern in ECG.