long gnrh agonist versus gnrh antagonist protocols in women with endometrioma and good ovarian reserve undergoing ivf/icsi cycles

Background: the best ovarian stimulation protocol in the case of endometrioma-related infertility is still debated. in this study, we examined the effect of two ovarian stimulation protocols on in vitro fertilization (ivf)/intra-cytoplasmic sperm injection (icsi) outcome in patients with good ovarian reserve suffering from endometrioma.methods: in a retrospective study, 101 women with endometrioma and good ovarian reserve were recruited. women received either gonadotropin-releasing hormone (gnrh) agonists (n=65) or gnrh antagonists (n=36) in an ivf or icsi cycle. clinical and chemical pregnancy rate, live birth rate, implantation rate, fertilization rate and fertilization proportion, as well as miscarriage rate, were evaluated in both groups.results: chemical (25% vs. 28.6%), clinical (19.6% vs. 25%), and live birth rates (19.6% vs. 25%) as well as implantation rate (11.7% vs. 15%) were not significantly different between the two groups. miscarriage rate, fertilization rate and fertilization proportion were similar in the two groups.conclusion: gnrh antagonist protocol with the main advantages of short duration and lower cost of treatment could be applied in infertile patients with endometrioma and good ovarian reserve.