molecular and phenotypic characteristics of staphylococcus hominis isolates from pediatric infections

Background: em staphylococcus hominis /em has been recently emerged as an opportunistic hospitalassociated pathogen. the aim of this study was to characterize the antimicrobial susceptibility pattern, biofilm formation, and staphylococcal cassette chromosome em mec /em (scc em mec /em ) types among clinical isolates of em s. hominis /em obtained from pediatric infections. methods: totally, twenty two clinically significant em s. hominis /em isolates, mostly from blood samples, were examined for antibiotic resistance, scc em mec /em typing, and biofilm formation.  results: multiresistance was observed in 86 % of isolates. among em mec /em a positive isolates (77%), scc em mec /em type i (28%), iii (22%), iv (22%), and nontypeable ones (28%) were detected. more than half of the isolates (54.5%) did not produce biofilm. no significant association was found between biofilm formation and the presence of em ica /em operon. conclusion: as em s. hominis /em isolates were not strong biofilm producers, biofilm formation cannot be considered as much as important multidrug resistance.in the pathogenesis of isolates.