TB/ HIV co-infection

The vicious interaction between the humanimmunodeficiency virus (hiv) infection andtuberculosis (tb) pandemics poses specialchallenges to national control programs andindividual physicians. although recommendationsfor the treatments of tb in hiv-infected patientsdo not significantly differ from those for hivuninfectedpatients, the appropriate management ofhiv-associated tb is complicated by healthsystem issues, diagnostic difficulties, adherenceconcerns, overlapping adverse-effect profiles anddrug interactions, and the occurrence ofparadoxical reactions after the initiation ofeffective antiretroviral therapy.