Report of a case with congenital candidiasis

Background: Osteoarthritis(OA) is the most common disease of the synovial joints, especially inprofessional athletes. Endurance training causes OA in joints, particularlytheir knee joint. Theaim of the present study was to investigate the effect of volume and intensityof two different types of endurance training on the incidence of knee OA inhealthy male rats. Methods: In this experimental study, 24 rats were randomlydivided into three groups of control, endurance 1 and endurance 2. The exercise included five days and a total of eightweeks of endurance exercise, including one hour intensity endurancerunning %50 to %55 percent for endurance 1 group, and for endurance 2,halfhour run with %70 to 75% of the oxygen consumed. In order to investigate  osteoarthritis, 24 hours after the lasttraining session, joint sample tissueswere collected. The amount of joint damage was evaluated by histopathology andmethod was compared with oneway ANOVA analysis. Results: Theresults showed that none of the groups had no significant influence on theincrease in cartilage thickness (p = 0.20). Also, an hour of endurance trainingcaused moderate OA (grade 3) in the rat knee (p = 0.002) , but in the endurancetraining group with 30 minutes training moderate OA (grade II), (p = 0.002) wasobserved. Conclusion: The results of this study showed that endurance training increased risk ofknee OA. Reducing the volume of exercise is an appropriate way to reduce theamount of damage