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facile fabrication and characterization of silver nanoparticles by sunn pest (eurygaster integriceps puton) damaged wheat and evaluation of its antibacterial and cellular toxicity toward liver cancer cell lines
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نویسنده
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nateq golestan mohammad ,abbasi mohammad reza ,rakhshandeh hasan ,taghavizadeh yazdi mohammad ehsan
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منبع
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مطالعات علوم پزشكي - 1402 - دوره : 34 - شماره : 10 - صفحه:586 -597
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چکیده
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Background & aims: silver nanoparticles (agnps) are among the most explored nanomaterials and are widely employed in medical, pharmaceutical, and bioengineering application. the aim of this study was to investigate the antibacterial and cell toxicity effects of fabricated agnps by green method at room temperature.materials & methods: in this work, agnps were fabricated by green method, which uses the seed extract of triticum aestivum damaged by sunn pest (eurygaster integriceps puton) (spdspdwagnps) at room temperature. powder x-ray diffraction (pxrd) and transmission electron microscopy (tem) were used for characterization of synthesized nanoparticles. disk diffusion method and mtt analysis were used for antibacterial and cell toxicity effects, respectively.results: the synthesis of spdspdwagnps was relevant by color change of solution, turning from light-yellow to dark-brown, respectively. α-glycosidase, protease and α-amylase are some identified enzymes of salivary glands of sunn pest which can affect the synthesis of nanoparticles. the results showed that spdspdwagnps have spherical shapes and had a different range from 1 to 25 nm. moreover, the biosynthesized spdspdwagnps have high antibacterial properties toward the most common inflectional bacteria. furthermore, the cytotoxicity results show the fabricated spdspdwagnps prevent the growth of cancer cells. conclusion: we concluded that this production manner of nanoparticles could be employed for large-scale synthesis of agnps, pharmaceutical, and antiseptic uses.
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کلیدواژه
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silver nanoparticle ,anticancer ,antimicrobial ,green chemistry
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آدرس
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agricultural research,education and extension organization(areeo), khorasan razavi agricultural and natural resources research and education center, plant protection research department, iran, agricultural research,education and extension organization(areeo), agricultural and natural resources research center of khorasan-e razavi, iran, mashhad university of medical sciences, pharmacological research center of medicinal plants, iran, mashhad university of medical sciences, applied biomedical research center, iran
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پست الکترونیکی
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metyazdi@gmail.com
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facile fabrication and characterization of silver nanoparticles by sunn pest (eurygaster integriceps puton) damaged wheat and evaluation of its antibacterial and cellular toxicity toward liver cancer cell lines
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Authors
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Abstract
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background & aims: silver nanoparticles (agnps) are among the most explored nanomaterials and are widely employed in medical, pharmaceutical, and bioengineering application. the aim of this study was to investigate the antibacterial and cell toxicity effects of fabricated agnps by green method at room temperature.materials & methods: in this work, agnps were fabricated by green method, which uses the seed extract of triticum aestivum damaged by sunn pest (eurygaster integriceps puton) (spdspdwagnps) at room temperature. powder x-ray diffraction (pxrd) and transmission electron microscopy (tem) were used for characterization of synthesized nanoparticles. disk diffusion method and mtt analysis were used for antibacterial and cell toxicity effects, respectively.results: the synthesis of spdspdwagnps was relevant by color change of solution, turning from light-yellow to dark-brown, respectively. α-glycosidase, protease and α-amylase are some identified enzymes of salivary glands of sunn pest which can affect the synthesis of nanoparticles. the results showed that spdspdwagnps have spherical shapes and had a different range from 1 to 25 nm. moreover, the biosynthesized spdspdwagnps have high antibacterial properties toward the most common inflectional bacteria. furthermore, the cytotoxicity results show the fabricated spdspdwagnps prevent the growth of cancer cells. conclusion: we concluded that this production manner of nanoparticles could be employed for large-scale synthesis of agnps, pharmaceutical, and antiseptic uses.
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Keywords
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silver nanoparticle ,anticancer ,antimicrobial ,green chemistry
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