effects of resistance training and retraining on creatine kinase, lactate dehydrogenase, and aspartate aminotransferase enzymes in inactive young boys

Purpose: unusual or intense exercise causes minor damage (microtrauma) to muscle fibers. it is thought that this damage is accompanied by the release of certain enzymes into the blood serum. the aim of the present study was to investigate the effect of resistance training and retraining on the enzymes creatine kinase, lactate dehydrogenase, and aspartate aminotransferase in inactive young boys. method: twenty-four healthy inactive young boys volunteered for the present study and were randomly divided into two groups of 10. the exercise protocol consisted of five stations of biceps and shoulders with a barbell, squats, chest presses, and forearm presses. each movement consisted of three sets of 12 repetitions. the exercise intensity was 75% of one repetition maximum. serum levels of the enzymes creatine kinase, lactate dehydrogenase, and aspartate aminotransferase were measured before the activity and at intervals of 1 and 48 hours thereafter. for data analysis, repeated measures analysis of variance and independent t-test were used at a significance level of p≥0.05. results: the results of the present study showed that the levels of creatine kinase, lactate dehydrogenase, and aspartate aminotransferase enzymes increased in both resistance training and resistance retraining groups compared to the pre-test at time intervals of 1, and 48. no differences were observed in serum levels of creatine kinase, lactate dehydrogenase, and aspartate aminotransferase between the two groups during and after retraining (p>0.05). conclusion: retraining may not be a significant variable affecting recovery after muscle injury. however, more research is needed in this area.