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serum ctrp1 levels in candidates for coronary artery bypass graft
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نویسنده
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pourghadamyari hossein ,ramazani-karim zohreh ,hajializadeh mohammad ,sajadi moghadam esmaeil ,borji hossein ,ahmadirad hadis ,sadeghi asie
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منبع
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acta biochimica iranica - 2025 - دوره : 3 - شماره : 2 - صفحه:120 -124
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چکیده
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Background: ctrp1 is an adipokine that plays crucial roles in the cardiovascular system, and its dysregulation has been reported in patients with cad. in this study, our aim was to measure its levels in patients who were candidates for cardiac bypass surgery.methods: the participants consisted of 30 candidates for coronary artery bypass graft (cabg) surgery and an additional 30 controls. inflammatory parameters were assessed using enzyme-linked immunosorbent assay (elisa) kits. serum ctrp1 concentration was determined using a commercially available elisa kit.results: serum ctrp1 levels significantly increased in the patient group compared to the control group (p-value < 0.0001). furthermore, ctrp1 levels positively correlated with inflammatory parameters.conclusion: elevated levels of ctrp1, along with inflammation in cad, suggest the involvement of ctrp1 in inflammatory responses. however, this hypothesis remains to be fully elucidated.
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کلیدواژه
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coronary artery bypass graft ,ctrp1 ,il-6 ,tnf-α ,hs-crp
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آدرس
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kerman university of medical sciences, applied cellular and molecular research center, faculty of medicine, department of clinical biochemistry, iran, kerman university of medical sciences, faculty of medicine, department of clinical biochemistry, iran, kerman university of medical sciences, school of medicine, iran, bam university of medical sciences, school of nursing and midwifery, department of nursing, iran, kerman university of medical sciences, shafa hospital, department of cardiac surgery, iran, rafsanjan university of medical sciences, pistachio safety research center, iran, kerman university of medical sciences, faculty of medicine, department of clinical biochemistry, iran
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پست الکترونیکی
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asiesadeghi@gmail.com
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Authors
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