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new flour link cupper-vanadium mixed ligand-mixed metal coordination polymers, synthesis, characterization, biological and thermal studies
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نویسنده
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musevi seyid javad ,aslani alireza
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منبع
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چهارمين كنفرانس ملي شيمي كاربردي ايران - 1398 - دوره : 4 - چهارمین کنفرانس ملی شیمی کاربردی ایران - کد همایش: 98190-11302 - صفحه:0 -0
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چکیده
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Anticancer cells and antimicrobial activity of new mixed metal 〖[cu_2 〖(bpa)〗_2 〖(vof_5)〗_2]〗_n complex (bpa = 2,2-bipyridineamine) at bulk and nano-sized have been studied and these new unusually structure complex characterized by elemental analysis, ir spectroscopy and its structures studied by single crystal x-ray crystallography. nanopowder of this compound synthesized by sonochemical method then characterized by x-ray diffraction (xrd), scanning electron microscopy (sem).these synthesized cp and ncp (cp = coordination polymers and ncp = nano coordination polymers) of fluoride link copper-vanadium with 2,2-bipyridine amine, as ligand, after being subjected to biological tests, showed anticancer activity. as ligand bpa is biologically active, the results of biological activity are as expected specifically, an activity was demonstrated in breast cancer cells (mcf7 and mda mb 231) and proliferative cells (mcf7).
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کلیدواژه
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cu(ii) ,vanadium ,antitumor ,nano coordination polymers
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آدرس
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, iran, , iran
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new flour link cupper-vanadium mixed ligand-mixed metal coordination polymers, synthesis, characterization, biological and thermal studies
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Authors
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Abstract
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anticancer cells and antimicrobial activity of new mixed metal 〖[cu_2 〖(bpa)〗_2 〖(vof_5)〗_2]〗_n complex (bpa = 2,2-bipyridineamine) at bulk and nano-sized have been studied and these new unusually structure complex characterized by elemental analysis, ir spectroscopy and its structures studied by single crystal x-ray crystallography. nanopowder of this compound synthesized by sonochemical method then characterized by x-ray diffraction (xrd), scanning electron microscopy (sem).these synthesized cp and ncp (cp = coordination polymers and ncp = nano coordination polymers) of fluoride link copper-vanadium with 2,2-bipyridine amine, as ligand, after being subjected to biological tests, showed anticancer activity. as ligand bpa is biologically active, the results of biological activity are as expected specifically, an activity was demonstrated in breast cancer cells (mcf7 and mda mb 231) and proliferative cells (mcf7).
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Keywords
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cu(ii) ,vanadium ,antitumor ,nano coordination polymers
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