green synthesis of fe3o4-mnps using clover leaf extract as efficient nanocatalyst for the synthesis of pyrido[2,1a]isoquinolines

In this work, synthesis of pyrido[2,1-a]isoquinolines in excellent yield using multicomponent reaction of phthalaldehyde, methyl amine, methyl malonyl chloride,alkyl bromides and triphenylphosphine in the presense of catalytic amount of fe3o4-mnps and aqueous sodium hydroxide at 80oc were investigated. the reduction of ferric chloride solution with clover leaf water extract caused to synthesis of magnetic iron oxide nanoparticles (fe3o4-nps) as a green method.