graphene oxide nanosheets supported n-heterocyclic cu(ii) complex for the synthesis of n-benzyl-n-aryl-5-amino-1h-tetrazoles

Tetrazoles, one of the versatile class of n-rich heterocycles, have attracted increasing attention over the past years owing to their exceptional properties (e.g. highest acidity, highest number of n atoms with well-stability, high formation enthalpy, maximum dipole moment, and lowest basicity) and widespread applications (e.g. medicinal, biological, and industrial) [1,2]. they occupied the superior place in severe research activity due to their exceptional properties/features in the pharmaceutical as isosteres/lipophilic spacers, in the coordination chemistry as ligands, and in the material science as rocket propellants/explosives/gas generators [1-3]. in this work, we have reported immobilization of 5-(4-bromophenyl) amino-1h-tetrazole-copper(ii) complex on the surface of graphene oxide nanosheets (gons) as catalyst towards the synthesis of n-benzyl-n-aryl-5-amino-1h-tetrazoles via [2+3] cycloaddition reaction of as-prepared n-benzylarylcyanamides with nan3. the structural features of nanocatalyst (gons-tet-cu(ii)) were investigated by ft/ir, (hr)tem, fesem, xrd, tg/dtg, eds and elemental mapping. ft/ir, 1h, 13c and 15n nmr were used to characterize the synthesized products. besides, the gons-tet-cu(ii) nanocatalyst could be reused up to eight successive cycles.