mixed ligand metal-organic frameworks of zr-mofs for 3-crs synthesis pyrazolophthalazine boosting sono-power

Zirconium cluster based mofs because of their good thermal and chemical stability in acid, water and a number of organic solvents [1, 2]. different formative of these frameworks are provided with ligands containing different functional groups such as hydroxyls, amines, nitrogen and halogens [3]. uio-66 is a zirconium-based network that is used most often and consists of cationic zr6o4(oh)4 heads (from the in situ hydrolysis of zrcl4) with benzenedicarboxylate, thus can function as a favourable support for encapsulating active catalytic species. herein, mixed ligand metal-organic frameworks of zirconium (uio-66) containing terephthalic acid (h2bdc) and 2-amino terephthalic acid (h2bdc/nh2) ligands were prepared under ultrasound irradiation. ft-ir analysis, scanning electron microscope (sem), x-ray diffraction, and edx were incorporated for the characterization of mofs. then, the zr-mofs represented a green and highly reusable catalyst for the ultrasound-assisted one pot synthesis of pyrazolophthalazine derivatives. the mild reaction condition, high yield, easy product separation and catalyst reusability for 6 cycles were the outstanding features of this method.