thermo-responsive polymeric micelle based on poly (n-isopropyl acrylamide-b-lauryl acrylate) (pnipam-b-pla) loaded au nanoparticles as an efficient catalyst for the reduction of nitroarenes

Structurally diverse anilines constitute major building blocks and key intermediates for the production of drugs, pharmaceuticals, pigments, dyes, and agrochemicals [1,2]. the typical route for their production is the selective reduction of the corresponding nitro-derivatives. catalytic reduction using metal catalysts is a well-established technique and often regarded as the method of choice for the reduction of nitroarenes to anilines [3]. herein, the preparation and characterization of thermo-responsive p(nipam-b-la)/au nanoparticles is reported. using thermo-responsive polymer to load au nanoparticles lead to prepare “smart” catalyst that its catalytic activity can be switched 'on' and 'off' below and above the lower critical solution temperature of polymeric micelle respectively in the reduction of nitroarenes.