synthesis azo a-amino phosphonate by formic acid catalyst

Aminophosphonates and their derivatives have a wide range of pharmaceutical applications as an important ingredient in organic compounds and used as anti-viral, antifungal, and anti-tumor. in this study, a new composition of dimethyl (phenyl) (4-phenyldienzylene) phenyl) amino (methyl) phosphonate and its derivatives was synthesized from the reaction of 4-amino-azobenzene and dimethyl phosphite and benzaldehyde derivatives in ethanol solvent (meoh) and in the presence of formic acid catalyst at 65 ° c in this work, formic acid as an effective green catalyst in the synthesis of aminophosphonates in the reaction kebchnik-fields was used. this catalyst synthesizes a-aminophosphonates in a short time under mild conditions. this catalyst can synthesize a-aminophosphonates with different aldehydes and ketones. the benefits of formic acid catalysts can be safe, non-toxic and affordable in this synthesis the process of separating the product from the reaction mixture is simple and can be accomplished in a short time. solvent removal and reactionat room temperature other advantagesuse of formic acid catalyst.all of the products obtained by ft-ir.uv-vis.h nmr.c nmr methods were investigated and their biological properties were investigated.