development of molecularly imprinted polymer on ferric oxide nanoparticles modified electrode as electrochemical sensor for detection of the amount of human chorionic gonadotropin (hcg)

A novel molecularly imprintedelectrochemical sensor based on ferricoxide nanoparticles modified glassycarbon electrode was fabricated fordetection of human chorionic gonadotropin(hcg). the stable proteins molecularlyimprinted polymer films were made byelectro-polymerization using aniline asfunctional monomer and hcg as thetemplate. according to the results, thesensor showed a linear range from 1.0 ×10−10 to 1.0 × 10−7 g/cm3 of hcg(r2=0.9588) under optimal conditions witha detection limit of 0.6 × 10−10 g/cm3. thecalibration curve showed a 95.8%correlation of the data. in conclusion, thesensor has sensitivity, high stability andgood repeatability.