semiempirical quantum calculations of chiral pillararene decorated with alpha- hydroxyglycine for enantioseparation of d-glucose and l-glucose

Glucose, consumed widely every day, has two l and d enantiomers. the semiempirical pm7 method was utilized to investigate enantiomer separation of glucose with different enantioselective pillararenes. also, alpha-hydroxyglycine- pillar[6]arene (ahgp6) has been introduced as a new glucose enantioselective molecule, and the separation of glucose enantiomers by differently decorated pillararene has been calculated. also, the effect of pillararenes’ ring size on the enantioseparation has been investigated.