molecular features of interaction between vegfr-2 and linifanib and semaxanib using a combination of computational methods

Due to the importance of vascular endothelial growth factor receptor type 2 (vegfr-2) in angiogenesis of cancerous tumors, in this work, the molecular mechanism of interaction between the vegfr-2 and linifanib and semaxanib as inhibitor was investigated using the molecular docking, molecular dynamics (md) simulation. for this purpose, post md analysis (structural and thermodynamics) were .performed