covalent triazine-based framework as a ph-dependent sustained-release nanocarrier for anticancer drug

A novel triazine covalent framework (ctf) as a nanostructure polymeric carrier was introduced for anticancer drug delivery. the morphology and molecular structure the synthesized ctf were characterized by different techniques such as ft-ir spectra, x-ray diffraction, elemental analysis, and nitrogen adsorption/desorption isotherm techniques. high specific surface area and porosity allowed us to achieve drug loading and encapsulation efficiency as high as 82% and 96%, respectively. the in vitro drug release study of anticancer drug loaded ctf showed a ph-dependent release behavior in which acidic ph accelerated drug release compared with the neutral ph. thus, the synthesized ctf could be as a great promise toward anti-cancer drug carrier.