preparation of tosyl cellulose acetate nanoparticles via nanoprecipitation

Cellulose acetate was synthesized with different degrees of substitution of acetyl and tosyl groups. nanoparticles of synthesized polymers were prepared via nanoprecipitation method. the effect of the degree of substitution groups and the order of addition on the size and shape of prepared nanoparticles were investigated. the smallest nanospheres (54 nm) were obtained from the tosyl cellulose acetate containing 1.94 acetyl groups and 0.54 tosyl groups per unit of glucose and by adding solution to water.