numerical simulation of drug delivery through the skin

. drug delivery through reservoir-based microneedle has become very important due to its non-invasiveness and the ability to deliver a wide range of drugs. in thispaper, we consider a system of partial differential equations to describe the transportof bound drug, free drug and water in the reservoir, microneedle, skin and blood vessel. the system of equations is completed with interface boundary conditions, initialand boundary conditions. the initial and boundary value problem is studied from anumerical point of view for qualitative behaviour