the relationship between serum 25-hydroxyvitamin d level and stage and grade of breast cancer in female patients referred to amir al-momenin hospital, zabol

Background & objective: breast cancer is one of the most common cancers in women worldwide. therefore, the present study was conducted with aim to examine the relationship between the serum level of 25-hydroxyvitamin d and the stage and grade of breast cancer in female patients referred to amir al-momenin hospital in zabol in 2023.materials & methods: this descriptive and analytic study was conducted in 2023 on 27 cases of breast cancer with 27 matched controls. information on breast cancer risk factors, vitamin d and calcium supplementation, and previous history of the disease was obtained by completing a general questionnaire. the blood samples were taken from the studied women and the concentration of 25-hydroxyvitamin d in the serum was measured by quantitative luminescence method. then, data were recorded and entered spss software for statistical analysis and evaluated using chi-square test. p<0.05 was considered significant.results: in this study, 6 people (22.2%) had mixed invasive ductal, 19(70.4%) had invasive ductal carcinoma, and 2(7.4%) had mucinous carcinoma. in terms of the degree of breast cancer, 3 people (11.1%) were of mild type, 18(66.7%) moderate type and 6 (22.2%) severe type of breast cancer.conclusion: no significant difference was observed between the serum level of 25-hydroxyvitamin d and different degrees of breast cancer. deficiency of vitamin d in women is a health problem that should be addressed by public health professionals.