comparison of serum level of vitamin d in pregnant women with preeclampsia and a control group in ayatollah mousavi hospital in zanjan

Background & objective: conflicting results have been reported about the association between vitamin d and preeclampsia. the aim of the current study is to compare the serum levels of vitamin d in preeclamptic, and non-preeclamptic pregnant women admitted to the ayatollah mousavi hospital in zanjan. materials & methods: in this case-control study, 120 pregnant women were selected using convenience sampling in zanjan in 2018-2019. then they were divided into two groups, preeclampsia and non- preeclampsia. both groups were matched one by one. the data were collected using a demographic information questionnaire and a researcher-made checklist. after obtaining consent from participants, blood samples were collected using the peripheral venous catheter. then the elisa test was used to measure vitamin d in participants. data were analyzed by spss version 16 using, independent t-test, and chi-square test (p≤0.05). results: of the participants, 64 (53.4 %) were between 20-35 years old, 48 (40%) were older than 35 years, and 8 (6%) were younger than 20 years. most of the participants' gestational age was between 34 and 39 weeks (89.1%). the mean (sd) of serum level of vitamin d was significantly higher in healthy pregnant women (19.06 (7.48)) than women with preeclampsia (16.60 (5.87)) (p<0.01). among those with preeclampsia, the highest vitamin d level (17.17) was observed at 37-39 weeks of gestation. the lowest level (10.8) was for those with less than 34 weeks gestational age. conclusion: this study demonstrated that vitamin d could be a protective factor for preeclampsia in pregnant women. however, further studies are recommended.