vaginal adenosis in two patients with no history of diethylstilbestrol: a case report

Introduction: vaginal adenosis is one of the precursor lesions of the vaginal clear cell adenocarcinoma (cca). the most common symptom of vaginal adenosis is abnormal vaginal pain and bleeding. about 90% of women exposed to diethylstilbestrol (des) during pregnancy have vaginal and cervical adenosis in female fetus. des has been reported rarely with no history of fetal use.case presentation: in this article, we report two vaginal adenosis patients with no history of des during pregnancy. there was no vaginal cancer in the follow-up of the patients.conclusion: vaginal adenosis is considered as a non-common differential diagnosis of vaginal bleeding that can be diagnosed by physical examination, colposcopy, and biopsy.