nico hydroxide nano-boxes as an electrode material for reduction of hydrogen peroxide

Abstract: the detection of h2o2 has attracted considerable attention as h2o2 plays an important role in medicine, food, pharmaceutical and environmental pollution, h2o2 is a catalytic by-product of a large number of oxidases, and the excessive of h2o2 could damage dna or proteins [1]. so, the analytical determination of h2o2 is of utmost importance in many different fields. transition metal oxide nanostructures are highly regarded by researchers in various fields of electrochemistry due to their attractive properties such as excellent electrochemical activity, ease of preparation, high physical stability, natural abundance and cost-effectiveness [2]. the hollow transition metal oxides nanostructures, as an important family of functional materials, in various applications such as energy storage systems and catalysis has been highly regarded by researchers due to their unique physical and chemical properties, i.e. high surface area, short diffusion pathways for electrons and ions, high electrochemical performance, high porosity etc [3]. here, uniform amorphous nico hydroxide nano-boxes with intact shell structure and nano-sizes were synthesized, while s2o32- was deliberately chosen as the coordinating etchant to the cu2o nanocubes templates under optimal reaction conditions. then, it was used to coat the surface of a glassy carbon electrode as an effective electrocatalyst for the reduction of hydrogen peroxide. this porous and three-dimensional structure provided abundant electrochemical active sites, high electrolyte/analyte availability, and high conductivity due to the synergistic effect of the bimetallic. as an amperometric h2o2 sensor, it shown a high sensitivity of 60 μa mm−1 cm−2 and wide linear range from 0.5 μm to 3 mm with a low detection limit of 0.16 μm. moreover, the developed sensor shown a great potential in determining h2o2 in biological real samples.