application of molybdenum schiff base complex and mwcnts in preparation of modified electrode for detection of acetaminophen and ascorbic acid

Abstract: the present work reports on a carbon-paste electrode (cpe) modified by incorporating schiff-base complex of molybdenum and multi-walled carbon nanotubes (mwcnt). the resulted modified electrode is used as a sensitive voltammetric sensor for determination of acetaminophen (ac) in the presence of ascorbic acid (aa) the electrode showed efficient electrocatalytic activity in lowering the anodic overpotentials and enhancement of the anodic currents. this electrode is able to completely resolve the voltammetric responses of aa and ac. the effects of potential sweep rate and ph of the buffer solution on the response of the electrode, toward aa and ac, and the peak resolution is thoroughly investigated by cyclic and differential pulse voltammetry (cv and dpv). the best peak resolution for these compounds (240 mv) using the modified electrode is obtained in solutions with ph 5.0. peak potential separation is resulted for two compounds. the modified electrode showed good sensitivity and selectivity. to the electrode has very good reproducibility (r.s.d.≤3%), high stability in its voltammetric response (more than two months without any considerable change in response) and low detection limit (sub micromolar) for ac in the presence of aa. the prepared electrode is successfully applied for the voltammetric detection of ac in pharmaceutical preparations