ionic liquid based magnetic needle headspace single-drop microextraction combined with high performance liquid chromatography for the determination of chlorophenols in wastewater

A magnetic needle headspace single-drop microextraction (mn-hs-sdme) method coupled to hplc/uv has been developed. trihexyl-(tetradecyl) phosphonium chloride was employed as an ionic liquid (il) solvent for the headspace extraction of some chlorophenol compounds from wastewater samples. despite of the non-magnetic character of the il, a significant improvement in the extraction efficiency was obtained by magnetization of the sdme needle using a pair of permanent disc magnets. a simplex method for the fast optimization of the experimental conditions (e.g, stirring speed, ionic strength, ph, extraction time, and temperature) was used. the coefficients of determination (r2) varied between 0.9943 and 0.9996, the limits of detection were from 0.004 to 0.007 µg ml-1 and, the recoveries were in the range of 88% to 120% for the studied analytes. the developed mn-hs-sdme hplc/uv method was successfully applied to the determination of chlorophenols in industrial wastewater.