preparation of zns/mos2 film grown on cellulose paper for determination of cardiac drugs from aqueous solutions by thin film microextraction method

In the current study, chemically modified cellulose paper was introduced as a novel extracting phase for thin film microextraction (tfme). zns/mos2 was used to modify the cellulose papers with hydrothermal conditions. the modified papers were evaluated as a sorbent for the extraction of digoxin medicine from aqueous samples. high-performance liquid chromatography was used for the quantification of the extracted compounds. teme parameters such as desorption condition, shaking rate, sample ionic strength and extraction time were investigated and optimized. limit of detections were good and relative standard deviations was low under the optimized condition. the calibration curves were obtained in the bigger range with a good linearity. human urine and blood plasma samples were studied as real samples for the evaluation of the method.