application of zinc based metal-organic framework reinforced porous hollow fiber for solid phase micro extraction of oxyfluorfene and ioxinyl toxins from environmental samples and quantification via hplc-uv

Zeolitic imidazolate framework 8 (zif-8) reinforced hollow fiber solid phase microextraction combined with high performance liquid chromatography (hplc) was used for the extraction and measurement of selective analytes including: ioxynil and oxyfluorfen in samples of garlic, onion and agricultural soil. the pores of the polypropylene fiber walls were filled by adsorbent with a simple, easy to use method and a very short time. the modified fiber was used to extract selective analytes and the extracted analytes were then eluted by using acetonitrile as the desorption solvent. the eluent was finally injected into hplc-uv. in order to achieve the highest extraction efficiency for the selected analytes in the hf-spme method, several parameters including extraction time, type of eluent, stirring rate, solvent volume and ph of sample solution were investigated for optimization [1]. in order to perform the optimization process, plackett–burman design (pbd) was performed. the box behnken design (bbd) method was used to identify the optimal point for the influencing parameters affecting the extraction efficiency [2]. according to the results of optimization, the relative standard deviation (rsd%) of the method for selected analytes was obtained lower than 5.5% [3]. finally, the method was successfully applied for the determination of the selected analytes in different types of garlic, onion and agricultural soil samples. based on the results, it can be stated that the method has the ability of the extraction of the intended analytes in real samples.