role of nurses in prevention from potential drug interactions in the intensive care unit

Aims: drug interactions include chemical reactions that often occur between two or more drugs or even when a drug is taken with food, drink, or a supplement. therefore, the aim of this current review is the determine potential drug interactions in the intensive care unit and the role of nurses in their prevention.information & methods: this is an integrated review. our available sources include all studies conducted on drug interactions in elderly care units between 2012 and 2024 that are included in this study. the databases searched include: cinahl, scopus, pubmed, cochrane database of systematic reviews, wiley, science direct, iran medex, scientific information database (sid), and google scholar. the persian-english keywords were drug interactions, potential drug interactions, “adverse events, “intensive care units, “critically units, “risk of drug coexistence”, “drug accident”, “adult” and “elderly”.findings: using the relevant keywords, 34 studies were found. 17 articles were excluded due to the lack of relevance to the topic and unavailability of the full text of the article. finally, 12 valid articles were confirmed, of which 6 were persian articles and 6 were in english.conclusion: drug interactions have a direct relationship with low apgar scores, age, long-term stays in the department, and the number of doctors. phenytoin, phenobarbital, and fentanyl are identified as the most interfering in the department.