polyethylene glycol-based materials: transformative applications in biomedicine and the food industry

Polyethylene glycol (peg) has emerged as a versatile polymer with widespread applications in both biomedical and food industries due to its unique physicochemical properties, including excellent biocompatibility, hydrophilicity, and ease of modification. in the biomedical field, peg-based materials have demonstrated remarkable potential in drug delivery systems, wound healing, and tissue engineering. peg hydrogels, in particular, have garnered significant attention for their ability to encapsulate and release therapeutic agents in a controlled manner, with stimuli-responsive systems offering tailored drug release mechanisms. in the food industry, peg-based materials are employed to enhance food quality, extend shelf life, and develop innovative packaging solutions, such as antimicrobial films and nanocomposites. this review comprehensively discusses the recent advancements in peg-based materials, focusing on their biomedical applications, including drug delivery and wound care, as well as their role in improving food safety and packaging. additionally, the challenges and limitations associated with peg, such as limited biodegradability and potential health concerns, are critically evaluated. finally, future perspectives on the development of nextgeneration peg-based materials, with an emphasis on sustainability and clinical translation, are highlighted.