znfe2o4@fe3o4 nanocatalyst for the synthesis of the 1,8-dioxooctahydroxanthene: antioxidant and antimicrobial studies

This study aims to prepare and evaluate the catalytic advantages of znfe2o4@fe3o4 in the synthesis of 1,8-dioxo-octahydroxanthene derivatives. the catalyst was prepared in two steps (1) preparation of zinc ferrite znfe2o4 and fe3o4 nanoparticles by co-precipitation technique (2) preparation of mixed metal oxide (znfe2o4@fe3o4). the catalyst was fully characterized by ftir, edx, xrd, fesem, tga, and vsm analyses. the znfe2o4@fe3o4 was applied as a catalyst for the 1,8-dioxo-octahydroxanthenes. the products were synthesized in significant yields (85–95%) in short reaction times (15–60 min) without laborious work-up. the biological activity of 1,8-dioxo-octahydroxant derivatives was studied. these compounds showed antioxidant activity between 64.4 and 90.2% and their antimicrobial activity against s. enterica, e. coli, l. monocytogenes, s. aureus, and e. faecalis was investigated.