quantification of langlois reagent by 19f-nmr spectroscopy

Sodium trifluoromethanesulfinate (natfms) is also known as “laglois reagent” developed quantitative 19f-nmr (qnmr) and also employed to determine the amounts of “laglois reagent” in a mixture containing (natfms) and other inorganic impurities, the amounts of natfms can be measured by high-performance liquid chromatography, but it requires a high-purity standard sample.  nmr signal was affecting the response to determined by measuring longitudinal relaxation time (t1) to be 1.2 s is the main parameter ‘‘delay time (d1) between two scans”. internal reference for the quantitative analysis was used as a trifluoroethanol of sodium trifluoromethane sulphinate by water as solvent. six experiments with different weights of sodium natfms/tfe and the relative standard deviation (r.s.d.) were repeated and the results are less than 2.0% and also detection limit of 19f-qnmr upto 0.85 mg. 19f-qnmr was calculated and the r.s.d.s of results were less than 2% of each mixture of amount natfms.