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   new developments in cancer treatment using cat t cell therapy, a kind of gene therapy  
   
نویسنده sohrabi azin ,saremi mahnaz
منبع personalized and precision medicine journal - 2024 - دوره : 9 - شماره : 32 - صفحه:1 -7
چکیده    Recent research has pinpointed cancer as the primary cause of death on a global scale. various traditional medications and cytotoxic immunotherapies have been established and are now accessible on the market. given the intricate nature of tumor activity and the multitude of genetic and cellular elements implicated in the development and spread of cancers, it is imperative to create a highly effective immunotherapy that can specifically target tumors at both the cellular and genetic levels. in the clinical context, cancer immunotherapy is growing more and more significant, particularly for tumors that are resistant to traditional chemotherapy and targeted treatments. chimeric antigen receptor (car) t cell therapy is a new method of modifying t cells taken from a patient’s blood in a laboratory setting. these modified t cells are created to express artificial receptors that specifically target a particular tumor antigen. these specifically recognize the tumor antigen without the participation of the major histocompatibility complex. the use of car therapy has the promise of providing a prompt and more secure treatment regimen for both non-solid and solid malignancies. this study provides a comprehensive analysis of the benefits and progress made in car immunotherapy.
کلیدواژه chimeric antigen receptor ,solid tumors ,immunotherapy ,cancer
آدرس islamic azad university, east tehran branch, faculty of basic sciences, department of biology, iran, ministry of health and medical education, reference health laboratory, iran
پست الکترونیکی mahnaz_saremi@yahoo.com
 
     
   
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