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increased expression of the lnc h19 gene in the plasma of people with breast cancer
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نویسنده
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mohammadi kazhaleh ,shojaei baghini sadegh ,saremi mohammad ali
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منبع
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personalized and precision medicine journal - 2020 - دوره : 5 - شماره : 17 - صفحه:12 -14
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چکیده
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The majority of ncrnas are known as long non-coding rnas (lncrnas) whose length exceeds 200 nucleotides. h19, a lncrna, is the transcription product of the h19 gene, an oncogene in breast cancer, and is highly expressed in cancer tissues compared with normal tissues. the expression level of h19 is associated with the oncogenesis, proliferation, invasion, metastasis, and drug resistance of breast cancer. h19 expression levels were detected in breast cancer plasma using qrt-real-time pcr assay in 50 breast cancer samples and 50 healthy control samples. the results showed that the expression of this gene in both the tissue and the plasma of patients increased compared to that of healthy individuals.
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کلیدواژه
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lncrnas ,breast cancer ,gene expression ,plasma ,qrt-real-time pcr
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آدرس
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knowledge university, medical laboratory science department, iraq, national institute of genetics engineering and biotechnology, plant biotechnology department, agriculture biotechnology department, iran, personalized medicine research center of amitisgen, iran
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پست الکترونیکی
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masaremi@yahoo.com
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Authors
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