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   your body on a chip: functional testing for personalized medicine  
   
نویسنده bora jumi ,mazandarani aynaz ,aghassizadeh-sherbaf mona
منبع personalized and precision medicine journal - 2022 - دوره : 7 - شماره : 27 - صفحه:1 -7
چکیده    Despite the well-known high prevalence of failure in drug development, recent advancements in tissue engineering and microfabrication have helped to create microphysiological systems (mps), or &organs-on-chips,& which mimic the function of human organs. these &tissue chips& might be used for toxicity and drug screening tests, which could revolutionize the early phases of the drug development process. additionally, they may be utilized to simulate disease conditions, supplying new instruments for deciphering disease pathologies and causes and evaluating the efficacy of novel treatments. future clinical trials on chips might be utilized to assess novel medicines in both populations and individuals, opening the door for precision medicine. here, we’ll discuss tissue chips’ diverse potential and the difficulties in developing them.
کلیدواژه drug development ,tissue chips ,personalized medicine
آدرس the assam royal global university, department of zoology, india, university of mazandaran, faculty of basic sciences, department of biochemistry, iran, islamic azad university, east-tehran branch, faculty of basic sciences, department of microbiology, iran
پست الکترونیکی mona.aghassizadeh@gmail.com
 
     
   
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