fabrication and characterization of coelectrospun polycaprolactone/chitosan nanofibrous mats

Core-shell nanofibers were fabricated via coaxiall electrospinning using polycaprolactone (pcl) as the shell material and chitosan (cs) as the core material. the confirmation of core-shell structure of the electrospun nanofibers was performed by attenuated total reflectance fourier transform infrared spectroscopy (atr-ftir) and water contact angle (wca) measurements. the obtained results of ftir showed that the surface of the core-shell nanofibers is uniformly covered with pcl, and cs was successfully encapsulated by pcl. the morphological investigation was done by scanning electron macroscopy (sem) which showed beadfree ultrafine cs-pcl core-shell nanofibers. pcl composition in the as-spun core-shell nanofibers was determind by dsc analysis based on the latent heat of pcl which was 64.3%. in vitro degradation test showed that because of the presence of core material, the fibrous structure of core-shell mat was maintained and prevented from the collapse of structure. the fabricated cs-pcl core-shell nanofibers have potentials in some biomedical applications.