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Green and Efficient Synthesis of Baclofen
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نویسنده
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Fernandes Pearl Rhea ,Madnala Ashwini ,Donde Nisha ,Pawar Amit ,Sonawale Maryappa
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منبع
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Advanced Journal Of Chemistry-Section B: Natural Products And Medical Chemistry - 2022 - دوره : 4 - شماره : 2 - صفحه:158 -163
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چکیده
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Baclofen is a gamma amino butyric acid (gaba) agonist to relax skeletal muscles. it is especially effective in treating muscular spasticity. in this research, we now describe the synthesis of baclofen using a new approach which begins with 4- chlorobenzaldehyde. we have carried all reactions by the green method. it gives the better yield. the identity of this product was confirmed by spectral analysis and compared with the standard baclofen. new and eco-friendly approach was developed for the synthesis
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کلیدواژه
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Gaba Agonist ,4-Chlorobenzaldehyde ,Cyanohydrin ,Oxidizingagent ,Pyridinium ,Wittig Type Reaction ,Hydrolysis ,Reduction
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آدرس
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Milagres College, Department Of Food Nutrition And Dietetics, India, Sies College Of Arts, Science And Commerce Sion, India, Karmaveer Bhaurao Patil College, India, Karmaveer Bhaurao Patil College, India, Veer Wajekar Asc College Phunde, India
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پست الکترونیکی
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maryappacsonawale11@gmail.com
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Authors
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