Evaluation of Immunohistochemical Effects of Apoptotic Cells in the Brain and Liver of Chick Embryos By Injection of Aluminosilicate

Background and aim: zeolites are crystalline aluminosilicate structures that have a porous structure and have the ability to absorb and release fluids and molecules that have a good diameter. also, cationic exchanges are not subject to structural changes in the characteristics of zeolites [1]. the special physical and chemic virtues of zeolites have made them appropriate for industry, agriculture, veterinary and environmental applications. zeolite is used to absorb and remove contaminants in water treatment, reducing and eliminating ammonia and heavy metals in the environment in veterinary medicine zeolites are used as animal feed additive and control of the smell and moisture of pets (animal beds such as dogs and others).methods: eggs (120) were prepared from ross breeder chickens and randomly divided into 4 groups of 30 (one control group and three experimental groups). in the control group, 0.3 ml of the physiologic serum was injected, and in the experimental groups, 0.3 ml of the solution of nanozeolitis (5, 50, 100 mg / l) injected into egg albumin, then the eggs were incubated for 19 days. at the end of incubaton time, the immunohistochemical effects of apoptotic cells in the brain and liver were evaluated.results: the severity of immunohistochemical effects of fetal liver was increasing with increasing the prescribed dose and the severity of lesions in the treated group at a dose of 100 mg / kg was higher than other groups and there was a significant difference with other groups. in immunohistochemical examination (tunnel) of the liver of nanosuolite-treated fetuses, the percentage of apoptosis did not show a significant difference between the three groups.conclusion: the results showed that aluminosilicate endangers the viability of fetal liver cells and activates the apoptotic process.