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a mathematical model for prediction of controlled drug release from ring cap tablet
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DOR
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20.1001.2.9718091706.1397.16.1.213.0
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نویسنده
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abdekhodaei mj ,baghani elham
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منبع
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كنگره مهندسي شيمي - 1397 - دوره : 16 - شانزدهمین کنگره ملی مهندسی شیمی - کد همایش: 97180-91706
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چکیده
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Ring cap tablets are oral controlled release drug delivery systems these tablets modify the release of drug by using insoluble bands which are circumferentially applied to tablet a new two dimensional model has been developed to predic t the release of drug from these systems erosion takes place in several steps, but in most situations degradation appears to be controlling step and it is assumed as a first order reaction in this research tablets with different numbers, width, and place ment of bands are modeled and compared the results show a nearly constant release rate for tablet with 2 bands and this one is closer to zero order release this model can be a mathematical framework for future simulations
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کلیدواژه
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erosion ,degradation ,ring cap ,hydrolysis ,mathematical model ,drug delivery
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آدرس
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sharif university of technology, iran, sharif university of technology, iran
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Authors
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