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   ten years survival outcome of breast cancer patients among south indian population: a retrospective cohort study  
   
نویسنده r. sarathi ,s. sarumathy ,v.m. durai mavalavan ,selvaraj karthikeyan
منبع journal of medicinal and pharmaceutical chemistry research - 2025 - دوره : 7 - شماره : 9 - صفحه:1999 -2008
چکیده    In india, breast cancer is the most frequently diagnosed malignancy in women; however, there is a lack of research on long-term survival rates. long-term oncological outcomes in curable breast cancer patients were examined in this study. this study presents a retrospective cohort analysis of 250 patients with various stages of breast cancer who received curative primary treatment at a cancer facility in south india between 2013 and 2023.  final analysis included 250 breast cancer patients, with a median age of 51 years (range: 21 to 69 years). 84.8% of patients presented with early breast cancer disease (ebc), 15.2% exhibited locally advanced breast cancer disease (labc), and 28% had newly developed metastatic disease which requires surgical treatment. 53.6% of patients presented with hormone-sensitive tumors, 28% exhibited overexpression of the human epidermal growth factor-2 receptor (her-2), and 55% were diagnosed with triple-negative breast cancer tumors (tnbc).  after initial cancer treatment, the cohort had overall survival (os) rates of 95% at 5 years and 50% at 10-years. ebc and labc were associated with extended survival in multivariate analysis. early-stage disease and subsequent primary cancer treatment has better 10-year survival rates.
کلیدواژه breast cancer ,overall survival ,early stage breast cancer ,locally advanced breast cancer
آدرس srm institute of science and technology, srm college of pharmacy, faculty of medicine and health sciences, department of pharmacy practice, india, srm institute of science and technology, srm college of pharmacy, faculty of medicine and health sciences, department of pharmacy practice, india, srm medical college hospital and research centre, department of medical oncology, india, srm medical college hospital and research centre, department of medical oncology, india
 
     
   
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