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   evaluating peanut allergy using indonesian local peanut variety skin prick test as an alternative diagnostic tool in atopic dermatitis patients  
   
نویسنده damayanti ,prakoeswa cita rosita sigit ,anggraeni sylvia ,umborowati menul ayu ,triesayuningtyas dinar chieko ,arachman mochammad ayyub ,setyaningrum trisniartami ,jastika faradistiani rakhmawati
منبع journal of medicinal and pharmaceutical chemistry research - 2025 - دوره : 7 - شماره : 8 - صفحه:1579 -1590
چکیده    Atopic dermatitis (ad) is an inflammatory skin condition that causes itching and eczematous skin lesions over a long period. peanut allergy is an immunological reaction mediated by immunoglobulin e (ige) that often manifests in childhood and can cause anything from moderate skin reactions to anaphylaxis. this study evaluated the accuracy of a skin prick test (spt) using local peanut allergen extract compared with standard allergen extract in diagnosing peanut allergy or sensitization involving 30 adult atopic dermatitis patients. the patients underwent history taking and spt tests with local and standard allergen extracts at separate times at 1-week intervals. the local allergen extract was produced by dr. soetomo general academic hospital surabaya, indonesia. there were three patients with positive results from the standard peanut spt. meanwhile, no positive results were detected with the local peanut spt. the specificity of local peanut spt was 93.3%, while the negative predictive value was 100%. the compatibility of local peanut spt to the patient’s history was 93.33%, which consisted of patients with no previous history of peanut allergy who got negative results. the local peanut allergen extract for spt had reasonable specificity and can be considered an alternative diagnostic tool to exclude peanut allergy in ad.
کلیدواژه human and health ,sensitive skin ,skin prick test ,peanut allergy ,atopic dermatitis
آدرس universitas airlangga, faculty of medicine, department of dermatology venereology and aesthetic, indonesia, universitas airlangga, faculty of medicine, department of dermatology venereology and aesthetic, indonesia, universitas airlangga, faculty of medicine, department of dermatology venereology and aesthetic, indonesia, universitas airlangga, faculty of medicine, department of dermatology venereology and aesthetic, indonesia, universitas airlangga, faculty of medicine, department of dermatology venereology and aesthetic, indonesia, universitas airlangga, faculty of medicine, department of dermatology venereology and aesthetic, indonesia, universitas airlangga, faculty of medicine, department of dermatology venereology and aesthetic, indonesia, universitas brawijaya, faculty of medicine, indonesia
پست الکترونیکی faradistianirakhma@gmail.com
 
     
   
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