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impact of xylene exposure on blood profiles and neurotoxic symptoms among printing workers in surabaya
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نویسنده
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tualeka abdul rohim ,perumal velu ,novianti salsabila ,putro gurendro ,ruyani aceng ,sari dina keumala ,muhammad dimas rahadian aji ,rokhmah dewi ,mukarromah nur ,utami tri niswati ,wicaksono rizky rahadian ,rois rachmy rosyida ,maryiantari ellyza setya ,susmiati ,santjaka aris ,zurimi suardi ,rasako hairudin ,nendissa mintje maria ,eko nurmianto ,wibowo pipid ari ,hardi s. ikhram ,rachman rizaldy fathur ,salmah umi ,irawan roy januardi ,sunardi sunardi ,maharja rizky ,rahmania aisy ,akbar kurnia ardiansyah ,nisa s. farhana syahrotun ,faradisha jihan ,hariastuti iswari ,chahyadhi bachtiar ,handoko lukman
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منبع
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journal of medicinal and pharmaceutical chemistry research - 2025 - دوره : 7 - شماره : 8 - صفحه:1763 -1773
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چکیده
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Xylene exposure is influenced by worker characteristics and the quality of the work environment. this study aimed to investigate the relationship between xylene exposure, blood profiles, and neurotoxic complaints among printing workers in surabaya. an observational, cross-sectional design was employed, involving 30 workers who met the inclusion criteria. data collection methods included questionnaires, documentation, interviews, and measurements. the independent variables were the concentration of xylene in the work environment (used to assess the intake dose) and worker characteristics such as age, years of service, working hours, nutritional status, use of personal protective equipment (ppe), smoking habits, and exercise habits. the dependent variables included blood profiles (erythrocytes, platelets, leukocytes, ldl, and cholesterol) and neurotoxic complaints. the results revealed that xylene concentrations were still below the threshold limit value. a total of 16 workers (53.3%) reported experiencing neurotoxic complaints. blood profiles (erythrocytes, platelets, leukocytes, ldl, and cholesterol) remained within the normal range. statistically significant relationships were found between xylene intake dose and neurotoxic complaints, between xylene intake dose and blood profiles, and between worker characteristics and neurotoxic complaints. to mitigate risks, it is recommended that printing companies improve ventilation systems, ensure safe working environments, promote a culture of health and safety, conduct regular health checks, and provide appropriate ppe for workers.
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کلیدواژه
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xylene exposure ,blood parameters ,neurotoxic symptoms ,printing industry workers ,workplace safety
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آدرس
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airlangga university, public health faculty, department of occupational health and safety, indonesia, universiti putra malaysia, jabatan rekabentuk perindustrian fakulti rekabentuk dan senibina, malaysia, airlangga university, public health faculty, department of occupational health and safety, indonesia, national research and innovation agency, center research for public health and nutrition, indonesia, bengkulu university, faculty of teacher training and education, department of biology education, indonesia, universitas sumatera utara, faculty of medicine, tropical medicine program study, indonesia, universitas sebelas maret, faculty of agriculture, department of food science and technology, indonesia, university of jember, faculty of public health, department of health promotion and behavior science, indonesia, universitas muhammadiyah of surabaya, faculty of health sciences, indonesia, universitas islam negeri sumatera utara, department of occupational health and safety, indonesia, universitas islam lamongan, faculty of health sciences, environmental health study programme, indonesia, state university of malang, faculty of sport science, department of occupational safety and health, indonesia, health polytechnic of kerta cendekia, occupational health and safety study program, indonesia, kadiri university, faculty of health sciences, nursing program, indonesia, health polytechnic of the ministry of health semarang, indonesia, poltekkes kemenkes maluku, department of nursing, indonesia, poltekkes kemenkes maluku, department of nursing, indonesia, poltekkes kemenkes maluku, department of nursing, indonesia, institut teknologi sepuluh nopember, department of industrial and systems engineering, indonesia, stikes bhakti husada mulia madiun, indonesia, universitas muslim indonesia, faculty of public health, department of occupational health and safety, indonesia, politeknik kesehatan bhakti pertiwi husada cirebon, indonesia, university of north sumatra, faculty of public health, indonesia, universitas negeri surabaya, sports science faculty, sports science department, indonesia, universitas karya persada muna, department of occupational safety and health, indonesia, universitas sulawesi barat, fakultas ilmu kesehatan, program studi keselamatan dan kesehatan kerja, indonesia, universitas darussalam gontor, faculty of health science, department of occupational health and safety, indonesia, jember university, public health faculty, department of occupational health, indonesia, occupational health and safety, indonesia, sebelas maret university surakarta, vocational school, department of occupational safety and health, indonesia, representative of the national population and family planning board of east java province, indonesia, sebelas maret university surakarta, vocational school, department of occupational safety and health, indonesia, politeknik perkapalan negeri surabaya, indonesia
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Authors
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