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investigation of the effectiveness of nano impregnation of dentine tubules with a molecular complex of copper hydroxyapatite
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نویسنده
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esiev ruslan k. ,samvelyan andrey a. ,kliukina ekaterina i. ,gazaryants vita a. ,abdurakhmanova bikakhanum s. ,garibyan vartan s. ,guseynova khadizhat m. ,shishkova alina l. ,chistokletova violetta s. ,chernova viktoriya e.
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منبع
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journal of medicinal and pharmaceutical chemistry research - 2025 - دوره : 7 - شماره : 1 - صفحه:42 -50
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چکیده
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This study was conducted on the effectiveness of depoforesis of the molecular complex of copper hydroxyapatite (cu-ha) into dentine tubules. for the experiment, 24 permanent caries-affected teeth were selected, removed for various indications in patients aged 16 to 35 years. next, cu-ha nanoimpregnation was performed using galvanophoresis. after 3, 7, and 14 days, the condition of the tooth section was assessed using a scanning electron microscope. it was found that 85-92% of dentine tubules are obstructed within 14 days, while the penetration depth of cu-ha is 800 microns. thus, for the prevention of recurrent caries and pulpitis, it is advisable to carry out galvanophoresis during this period. it was noted that with the age of teeth, the effectiveness of nanoimpregnation of dentine with cu-ha decreases. in general, the content of copper, calcium, and sulfur in the teeth of patients aged 16-20 years is 17% higher than in 35-year-olds. the presence of carious lesions reduces the content of these minerals by an average of 22%.
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کلیدواژه
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copper hydroxyapatite; cu-ha; dentine nanoimpregnation; dentine tubules; caries; pulpitis; dentistry
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آدرس
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north ossetian state medical academy, faculty of dentistry, russia, north ossetian state university named after k. l. khetagurov, faculty of dentistry, russia, first moscow state medical university named after i. m. sechenov, institute of dentistry, russia, kuban state medical university, faculty of dentistry, russia, dagestan state medical university, faculty of medicine, russia, north ossetian state medical academy, faculty of dentistry, russia, dagestan state medical university, faculty of medicine, russia, volgograd state medical university, faculty of dentistry, russia, stavropol state medical university, faculty of medicine, department of therapy, russia, stavropol state medical university, faculty of medicine, department of therapy, russia
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پست الکترونیکی
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aaazuret@gmail.com
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Authors
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