|
|
|
|
in silico studies for the antihypertensive effect of hibiscus acid and related compounds from hibiscus sabdariffa
|
|
|
|
|
|
|
|
نویسنده
|
zheoat ahmed m. ,ali ali muhsen ,salem asmaa sabah ,hussain zainb ali ,alkareem amel ali ,al-zahy younis mohamed atiah
|
|
منبع
|
journal of medicinal and pharmaceutical chemistry research - 2025 - دوره : 7 - شماره : 3 - صفحه:473 -479
|
|
چکیده
|
The use of herbal medicines has been part of human culture for years. for example, hibiscus (hibiscus sabdariffa) is known for its use in the management of hypertension. pharmacological studies showed that hibiscus extract is indeed effective in controlling hypertension. this study investigates the effects of acidic constituents in hibiscus extract on several antihypertensive targets using in silico docking techniques. based on the results, we predict that hibiscus acid may affect human angiotensin-converting enzyme (hace), potentially responsible for the antihypertensive effect of hibiscus.
|
|
کلیدواژه
|
antihypertensive ,in silico docking techniques ,hibiscus acid ,hibiscus sabdariffa ,angiotensin converting enzyme (ace)
|
|
آدرس
|
al-manara college for medical sciences, department of pharmacy, iraq, university of kerbala, college of medicine, iraq, al-manara college for medical sciences, department of pharmacy, iraq, al-manara college for medical sciences, department of pharmacy, iraq, iraqi ministry of health, thi-qar health department, iraq, misan university, college of education, department of physics, iraq
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|